Lab Automation

The GRC’s ultra high-throughput screening (uHTS) system has unsurpassed screening capacity, accuracy, and flexibility.

Software determines the amount of time each sample will take during individual movements of the robot and the composite time for all samples to be assayed. Testing of the schedule begins with running the schedules for individual instruments, followed by testing of all instruments without reagents, and finally, testing of all instruments with water. Next, an experiment is run using all instruments and robotics integrated by the schedule with experimental controls. After the biological procedure and the instrumentation are validated, the assay is ready for compound screening. The growing library available for screening includes over 160,000 compounds.

Robot in Action

The uHTS ystem is equipped with:

• 6-axis robot arm for dispatching screening process,

• proprietary dispenser for handling various dispensing modes (250nL ~5uL),

• pintool with 1536 precision pins (50nL slot) for transferring compounds, and

• microplate CCD imager with various reading methods for reading assay result.